# Attribution

## BodyParts3D

BodyParts3D release 4.0 polygons under `assets/anatomy/obj/` are used as the default anatomical view.

- Source: Database Center for Life Science (DBCLS), BodyParts3D.
- License: Creative Commons Attribution-ShareAlike 2.1 Japan (CC BY-SA 2.1 Japan).
- License statement: https://dbarchive.biosciencedbc.jp/en/bodyparts3d/lic.html
- Data: https://dbarchive.biosciencedbc.jp/en/bodyparts3d/download.html
- Citation: Mitsuhashi N, Fujieda K, Tamura T, Kawamoto S, Takagi T, Okubo K. BodyParts3D: 3D structure database for anatomical concepts. Nucleic Acids Research 37, D782–D785 (2009).
- Local notice: `assets/anatomy/NOTICE.md`.

The viewer rotates the scene for display when the longest source axis is not vertical. The OBJ files are not rewritten. Share-alike covers adaptations of these meshes. It does not relicense `src/hdt`. Mesh identity is a BodyParts3D identifier (`BPxxxxx.obj`).

Z-Anatomy was not imported. A kidney source it cites is CC BY-NC 4.0 and is not in this repository.

## Pulse Physiology Engine

Pulse 4.4.0, tag `REL_4_4_0`, is an external whole-body physiology engine used when a scenario requests it. Kitware distributes Pulse under Apache-2.0. The local build and its transitive notices stay under `third_party/pulse-build/` and are not copied into `src/`. The exercise intensity used by the runtime is the dimensionless value from the Pulse `HowTo_Exercise.py` example.

## Three.js

Three.js r160 (`three`, `OBJLoader`, `OrbitControls`) is MIT licensed and vendored under `src/hdt/workbench/static/vendor/three/`.

## Physiology literature used by the local solvers

Jones HM, Rowland-Yeo K. Basic concepts in physiologically based pharmacokinetic modeling in drug discovery and development. CPT: Pharmacometrics & Systems Pharmacology 2, e63 (2013). The teaching-compound table is the drug model’s compartment set.

Guyton and Hall textbook anchors for GFR 125 mL/min, urine about 1 mL/min, sodium 142 mmol/L, and extracellular fluid about 15 L are used by organ-v1. They are anchors, not a fit to a subject.

Suga H, Sagawa K. Instantaneous pressure-volume relationships and their ratio in the excised, supported canine left ventricle. Circulation Research 35, 117–126 (1974), for the time-varying elastance form in independent-v1.

Wilkinson GR, Shand DG. A physiological approach to hepatic drug clearance. Clinical Pharmacology & Therapeutics 18, 377–390 (1975), for the well-stirred clearance form.

Irsigler, American Review of Respiratory Disease 1976. The independent engine uses the published mean rebreathing slope 2.60 L/min/mmHg with a 5 L/min intercept at 40 mmHg, and does not refit it. The 15 s lag is an assumption stated in `docs/independent-engine.md`.